| ncRNA name | HMGB1 siRNA |
| ncRNA Category | siRNA |
| Disease name | diabetic retinopathy (DR) |
| Species | Rattus norvegicus |
| Tissues/Cell_line | human retinal endothelial cells (HRECs) |
| Methods | siRNA transfection, ROS assay, T-SOD assay, MTT assay, flow cytometry, Hoechst 33342 staining |
| Expression pattern | associated |
| Functional description | HMGB1 siRNA can reduce retinal cell damage induced by high glucose in vitro and in vivo and delay DR progress through the HMGB1-IKKβ-NFκB signaling pathway. |
| PubMed ID | 28352154 |
| Year | 2017 |
| Title | HMGB1 siRNA can reduce damage to retinal cells induced by high glucose in vitro and in vivo. |
| Drug-related ncRNA | NO |
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